Equine metabolism of the growth hormone secretagogue MK‐0677 in vitro and in urine and plasma following oral administration

Author:

Cutler Charlotte12ORCID,Viljanto Marjaana1ORCID,Taylor Polly1,Habershon‐Butcher Jocelyn3,Van Eenoo Peter2

Affiliation:

1. LGC Ltd Fordham UK

2. Doping Control Laboratory Ghent University (Ugent) Ghent Belgium

3. British Horseracing Authority London UK

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Reference42 articles.

1. A Nonpeptidyl Growth Hormone Secretagogue

2. Oral administration of growth hormone (GH) releasing peptide‐mimetic MK‐677 stimulates the GH/insulin‐like growth factor‐I axis in selected GH‐deficient adults;Chapman IM;J Clin Endocrinol Metabol,1997

3. Adult growth hormone deficiency – benefits, side‐effects, and risks or growth hormone replacement;Reed ML;Front Endocrinol,2013

4. Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue.

5. Effects of oral administration of ibutamoren mesylate, a nonpeptide growth hormone secretagogue, on the growth hormone–insulin-like growth factor I axis in growth hormone–deficient children

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