Изучение метаболизма секретагога гормона роста ибутаморена (MK-677) в моче человека методом ультравысокоэффективной жидкостной хроматографии-масс-спектрометрии высокого разрешения
Author:
Affiliation:
1. Кубанский государственный университет
Publisher
The Russian Academy of Sciences
Reference20 articles.
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2. Patchett A.A., Nargund R.P., Tata J.R., Chen M.H., Barakat K.J., Johnston D.B., Cheng K., Chan W.W., Butler B., Hickey G. Design and biological activities of L-163,191 (MK-0677): A potent, orally active growth hormone secretagogue // Proc. Natl. Acad. Sci. USA. 1995. V. 92. № 15. P. 7001. https://doi.org/10.1073/pnas.92.15.7001
3. Ishida J., Saitoh M., Ebner N., Springer J., Anker S.D., von Haehling S. Growth hormone secretagogues: History, mechanism of action, and clinical development // JCSM Rapid Commun. 2020. V. 3. № 1. P. 25. https://doi.org/10.1002/rco2.9
4. Copinschi G., Van Onderbergen A., L’Hermite-Balériaux M., Mendel C.M., Caufriez A., Leproult R., Bolognese J.A., De Smet M., Thorner M.O., Van Cauter E. Effects of a 7-day treatment with a novel, orally active, growth hormone (GH) secretagogue, MK-677, on 24-hour GH profiles, insulin-like growth factor I, and adrenocortical function in normal young men // J. Clin. Endocrinol Metab. 1996. V. 81. № 8. P. 2776. https://doi.org/10.1210/jcem.81.8.8768828
5. Svensson J., Lönn L., Jansson J.O., Murphy G., Wyss D., Krupa D., Cerchio K., Polvino W., Gertz B., Boseaus I., Sjöström L., Bengtsson B.A. Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure // J. Clin. Endocrinol. Metab. 1998. V. 83. № 2. P. 362. https://doi.org/10.1210/jcem.83.2.4539
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