Rapid Tolerance to Constipating Effects of Loperamide in Healthy Subjects-Reference-Cited by-同舟云学术

Rapid Tolerance to Constipating Effects of Loperamide in Healthy Subjects

Published:2016-01-18 Issue:2 Volume:56 Page:248-249
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Kolbow Julia¹,Weitschies Werner²,Siegmund Werner¹

Affiliation:

1. Department of Clinical Pharmacology, Center of Drug Absorption and Transport; University Medicine; Greifswald Germany

2. Department of Pharmaceutical Technology and Biopharmacy, Center of Drug Absorption and Transport; University of Greifswald; Greifswald Germany

Funder

German Federal Ministry of Education and Research Grants InnoProfile

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcph.659/fullpdf

Reference7 articles.

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2. Mechanisms that underlie mu-opioid receptor agonist-induced constipation: differential involvement of mu-opioid receptor sites and responsible regions;Mori;J Pharmacol Exp Ther,2013

3. Opioid analgesics and P-glycoprotein efflux transporters: a potential systems-level contribution to analgesic tolerance;Mercer;Curr Top Med Chem,2011

4. Extended-release but not immediate-release and subcutaneous methylnaltrexone antagonizes the loperamide-induced delay of the whole-gut transit time in healthy subjects;Kolbow;J Clin Pharmacol,2016

5. Siegmund W Modess C Paulick A Wegner D Effects of extended release methylnaltrexone bromide (150 mg b.i.d.) in comparison to extended release naloxone hydrochloride (20 mg b.i.d.) on loperamide-induced delay of the oro-cecal, whole-gut and colon transit time in healthy subjects (EudraCT-No. 2011-000895-32) Clinical study report, University Medicine Greifswald, Department of Clinical Pharmacology 2012

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1. Gastrointestinal Transit and Hydrodynamics Under Fasting and Fed Conditions;Oral Drug Delivery for Modified Release Formulations;2022-04-08

2. Loperamide cardiotoxicity: “A Brief Review”;Annals of Noninvasive Electrocardiology;2017-11-10

3. “Poor man’s methadone” can kill the poor man. Extra-medical uses of loperamide: a review;Forensic Toxicology;2017-04-07