Visible Light Mediated Halogen Atom Transfer to Access Polyhalogenated and Deuterated Lactams from Alkyl Halides-Reference-Cited by-同舟云学术

Visible Light Mediated Halogen Atom Transfer to Access Polyhalogenated and Deuterated Lactams from Alkyl Halides

Published:2023-07-11 Issue:30 Volume:26 Page:
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur J Org Chem

Author:

Arora Shivani¹,Singh Tavinder¹,Mondal Umasankar¹,Singh Anand¹²^ORCID

Affiliation:

1. Department of Chemistry Indian Institute of Technology Kanpur Kanpur 208016, Uttar Pradesh India

2. Department of Sustainable Energy Engineering Indian Institute of Technology Kanpur Kanpur 208016, Uttar Pradesh India

Abstract

AbstractA visible light mediated protocol for the synthesis of polyhalogenated and deuterated δ‐ and γ‐lactams from readily available alkyl halides is reported. The reaction involves the generation of haloalkyl radicals through halogen atom transfer (XAT) and subsequent arylalkylation of olefins to afford dihydroisoquinolinones and oxindoles. This new XAT protocol exhibits wide scope under mild conditions and enables access to new halogenated chemical space.

Funder

Indian Institute of Technology Kanpur

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference77 articles.

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