Rhodium‐Catalysed Selective C−H Allylation of 1H‐Indazoles with Vinylethylene Carbonate: Easily Introducing Allylic Alcohol

Abstract

AbstractAn efficient rhodium(III)‐catalysed C−H activation of 3‐aryl‐1‐H‐indazoles with easily available vinylethylene carbonate has been reported. A series of allyl alcohol substituted 3‐aryl‐1‐H‐indazoles were obtained with broad functional groups tolerance and favourable stereoselectivity. Notably, C−H and C−O bonds were selectively activated in “one pot” manner, releasing CO2 as the sole by‐product and avoiding external oxidant. This protocol provides a powerful approach for the post stage C−H allylation of indazole‐based substrates.