Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design
Author:
Affiliation:
1. Department of Biochemistry; Duke University Medical Center; Durham North Carolina 27710
Publisher
Wiley
Subject
Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/pro.2411/fullpdf
Reference81 articles.
1. Current and future therapy of invasive fungal infections;Andriole;Curr Clin Top Infect Dis,1998
2. Clinical pharmacology of systemic antifungal agents: a comprehensive review of agents in clinical use, current investigational compounds, and putative targets for antifungal drug development;Groll;Adv Pharmacol,1998
3. Antifungal agents: chemotherapeutic targets and immunologic strategies;Georgopapadakou;Antimicrob Agents Chemother,1996
4. Emerging fungal threats to animal, plant and ecosystem health;Fisher;Nature,2012
5. Antifungal susceptibility testing: practical aspects and current challenges;Rex;Clin Microbiol Rev,2001
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