A Clinical Drug‐Drug Interaction Study Assessing a Novel Drug Transporter Phenotyping Cocktail With Adefovir, Sitagliptin, Metformin, Pitavastatin, and Digoxin-Reference-Cited by-同舟云学术

A Clinical Drug‐Drug Interaction Study Assessing a Novel Drug Transporter Phenotyping Cocktail With Adefovir, Sitagliptin, Metformin, Pitavastatin, and Digoxin

Published:2019-08-12 Issue:6 Volume:106 Page:1398-1407
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Trueck Christina¹,Hsin Chih‐hsuan¹,Scherf‐Clavel Oliver²,Schaeffeler Elke³⁴,Lenssen Rebekka⁵,Gazzaz Malaz¹⁶,Gersie Marleen¹,Taubert Max¹,Quasdorff Maria¹,Schwab Matthias⁴⁷⁸,Kinzig Martina²,Sörgel Fritz²⁹,Stoffel Marc S.¹,Fuhr Uwe¹

Affiliation:

1. University of Cologne, Faculty of Medicine and University Hospital CologneCenter for PharmacologyDepartment I of PharmacologyCologne Germany

2. Institute for Biomedical and Pharmaceutical Research Nürnberg‐Heroldsberg Germany

3. Dr. Margarete‐Fischer‐Bosch Institute of Clinical Pharmacology Stuttgart Germany

4. University of Tuebingen Tuebingen Germany

5. Hospital Pharmacy University Hospital Cologne Cologne Germany

6. Department of Clinical Pharmacy College of Pharmacy Umm Al‐Qura University Makkah Saudi Arabia

7. Department of Clinical Pharmacology University Hospital Tuebingen Tuebingen Germany

8. Department of Pharmacy and Biochemistry University of Tuebingen Tuebingen Germany

9. Institute of Pharmacology Faculty of Medicine University Duisburg‐Essen Essen Germany

Funder

Robert Bosch Stiftung

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.1564

Reference49 articles.

1. The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs

2. Transporter-mediated drug–drug interactions

3. US Food and Drug Administration (FDA).In vitro metabolism‐ and transporter‐ mediated drug‐drug interaction studies guidance for industry. Draft Guidance as of October 2017 (2017). Accessed January 25 2019.

4. European Medicines Agency (EMA).Guideline on the investigation of drug interactions CPMP/EWP/560/95/Rev. 1 Corr. 2** June 21 2012 (2012). Accessed January 25 2019.

5. Pharmacokinetic Phenotyping to Predict Drug-Drug Interactions: Time to Divorce the Hybrid Concept of Simultaneous Mechanistic-Based and Exposure-Based Assessment

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Effect of protein binding on the pharmacokinetics of the six substrates in the Basel phenotyping cocktail in healthy subjects and patients with liver cirrhosis;European Journal of Pharmaceutical Sciences;2024-11

2. Understanding plasma protein binding of drugs: Considering complexity and binding dynamics;Journal of Pharmaceutical Sciences;2024-09

3. Albumin-Mediated Drug Uptake by Organic Anion Transporter 1/3 Is Real: Implications for the Prediction of Active Renal Secretion Clearance;Molecular Pharmaceutics;2024-08-21

4. Investigation of the drug–drug interaction and incompatibility mechanism between Aconitum carmichaelii Debx and Pinellia ternata (Thunb.) Breit;Journal of Ethnopharmacology;2024-08

5. Innovative Approaches to Optimize Clinical Transporter Drug–Drug Interaction Studies;Pharmaceutics;2024-07-26