Andrographolide inhibits hypoxia-induced hypoxia-inducible factor 1α and endothelin 1 expression through the heme oxygenase 1/CO/cGMP/MKP-5 pathways in EA.hy926 cells

Author:

Lin Hung-Chih12,Su Shih-Li3456,Lin Wan-Chun7,Lin Ai-Hsuan7,Yang Ya-Chen8,Lii Chong-Kuei78,Chen Haw-Wen7

Affiliation:

1. Division of Neonatology, College of Medicine; Children's Hospital of China Medical University and China Medical University Hospital; Taichung Taiwan

2. Department of Pediatrics; Children's Hospital of China Medical University and China Medical University Hospital; Taichung Taiwan

3. Vascular and Genomic Center, Changhua Christian Hospital; Changhua Taiwan

4. Division of Endocrinology and Metabolism; Changhua Christian Hospital; Changhua Taiwan

5. Department of Internal Medicine; Changhua Christian Hospital; Changhua Taiwan

6. Institute of Medicine; Chung Shan Medical University; Taichung Taiwan

7. Department of Nutrition; China Medical University; Taichung Taiwan

8. Department of Health and Nutrition Biotechnology; Asia University; Taichung Taiwan

Funder

China Medical University

Asia University

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Management, Monitoring, Policy and Law,Toxicology,General Medicine

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