R248Q mutation-Beyond p53-DNA binding-Reference-Cited by-同舟云学术

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R248Q mutation-Beyond p53-DNA binding

Published:2015-10-27 Issue:12 Volume:83 Page:2240-2250
ISSN:0887-3585
Container-title:Proteins: Structure, Function, and Bioinformatics
language:en
Short-container-title:Proteins

Author:

Ng Jeremy W. K.¹²,Lama Dilraj²,Lukman Suryani²³,Lane David P.⁴,Verma Chandra S.¹²⁵,Sim Adelene Y. L.²

Affiliation:

1. Department of Biological Sciences; National University of Singapore; Singapore Republic of Singapore

2. Bioinformatics Institute, Agency for Science, Technology, and Research; Singapore Republic of Singapore

3. Department of Applied Mathematics and Sciences; Khalifa University of Science, Technology, and Research; Abu Dhabi UAE

4. p53 Laboratory; Agency for Science, Technology, and Research; Singapore Republic of Singapore

5. School of Biological Sciences; Nanyang Technological University; Singapore Republic of Singapore

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Reference53 articles.

1. Cancer. p53, guardian of the genome;Lane;Nature,1992

2. Surfing the p53 network;Vogelstein;Nature,2000

3. Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence;Li;Cell,2012

4. Mutations in the p53 gene occur in diverse human tumour types;Nigro;Nature,1989

5. p53 mutations in human cancers;Hollstein;Science,1991

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1. Application of prime editing system to introduce TP53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line;Cancer Science;2024-03-28

2. Knockdown of TFAP2E results in rapid G₂/M transition in oral squamous cell carcinoma cells;Oncology Letters;2024-01-29

3. Reactivation of mutant p53 in esophageal squamous cell carcinoma by isothiocyanate inhibits tumor growth;Frontiers in Pharmacology;2023-04-24

4. Unraveling the Structural Changes in the DNA-Binding Region of Tumor Protein p53 (TP53) upon Hotspot Mutation p53 Arg248 by Comparative Computational Approach;International Journal of Molecular Sciences;2022-12-07

5. Deciphering the mechanisms of HPV E6 mutations in the destabilization of E6/E6AP/p53 complex;Biophysical Journal;2022-05

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