Synthesis and metabolic profile of Cl-966: A potent, orally-active inhibitor of GABA uptake

Author:

Bjorge Susan,Black Ann,Bockbrader Howard,Chang Tsun,Gregor Vlad E.,Lobbestael Sandra J.,Nugiel David,Pavia Michael R.,Radulovic Louis,Woolf Thomas

Publisher

Wiley

Subject

Drug Discovery

Reference23 articles.

1. Orally Active and Potent Inhibitors of γ-Aminobutyric Acid Uptake

2. Synthetic analogs for the study of GABA as a neurotransmitter

3. and : N-substituted-piperidine-3-carboxylic or acetic acid derivatives are gamma-aminobutyric acid inhibitors. Sedatives and Analgesies US Patent 4,383,999, 1983.

4. Anticonvulsant activity of GABA uptake inhibitors and their prodrugs following central or systemic administration

5. : GABAergic transmission in the mammalian central nervous system. In and (eds.): ?GABA Neurotransmitters. Pharmacochemical, Biochemical and Pharmcological Aspects.? Copenhagen: Munksgaard, 1979, 17-27.

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