Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the Ci PA Initiative-Reference-Cited by-同舟云学术

Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the Ci PA Initiative

Published:2018-08-27 Issue:2 Volume:105 Page:466-475
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Li Zhihua¹,Ridder Bradley J.¹,Han Xiaomei¹,Wu Wendy W.¹,Sheng Jiansong¹,Tran Phu N.¹,Wu Min¹,Randolph Aaron¹,Johnstone Ross H.²,Mirams Gary R.³,Kuryshev Yuri⁴,Kramer James⁴,Wu Caiyun⁴,Crumb William J.⁵,Strauss David G.¹

Affiliation:

1. Division of Applied Regulatory Science Office of Clinical Pharmacology Office of Translational Sciences Center for Drug Evaluation and Research U.S. Food and Drug Administration Silver Spring Maryland USA

2. Department of Computer Science Healthcare Informatics University of Oxford Oxford UK

3. Centre for Mathematical Medicine & Biology School of Mathematical Sciences University of Nottingham Nottingham UK

4. Charles River Laboratories Wilmington Massachusetts USA

5. CytoBioscienceNew OrleansLouisianaUSA

Funder

U.S. Department of Energy

U.S. Food and Drug Administration

Wellcome Trust

Royal Society

Engineering and Physical Sciences Research Council

Roche

Publisher