Racemic and enantiopure forms of 3-ethyl-3-phenylpyrrolidin-2-one adopt very different crystal structures

Author:

Krivoshein Arcadius V.1ORCID,Lindeman Sergey V.2,Timofeeva Tatiana V.3,Khrustalev Victor N.34

Affiliation:

1. Department of Physical & Applied Sciences; University of Houston - Clear Lake; Houston Texas USA

2. Department of Chemistry; Marquette University; Milwaukee Wisconsin USA

3. Department of Chemistry; New Mexico Highlands University; Las Vegas New Mexico USA

4. Department of Inorganic Chemistry; Peoples' Friendship University of Russia; Moscow Russia

Funder

University of Houston - Clear Lake Faculty Research Support Fund

National Science Foundation - Division of Materials Research

Ministry of Education and Science of the Russian Federation

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

Reference30 articles.

1. Natural asymmetry, isomerism and pharmacological action;Pfeiffer;J Sci Ind Res,1967

2. Estimation of the burden of active and life-time epilepsy: A meta-analytic approach;Ngugi;Epilepsia,2010

3. Antiepileptic drugs based on the α-substituted amide group pharmacophore: From chemical crystallography to molecular pharmaceutics;Krivoshein;Curr Pharm Des,2016

4. Some 3,3-substituted-2-pyrrolidinones;Marshall;J Org Chem,1958

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