Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function

Author:

Van Der Steen Nele123,Keller Kaylee3,Dekker Henk3,Porcelli Letizia4,Honeywell Richard J.3,Van Meerloo Johan5,Musters René J. P.6,Kathmann Ietje3,Frampton Adam E.78ORCID,Liu Daniel S. K.7,Ruijtenbeek Rob9,Rolfo Christian110,Pauwels Patrick12,Giovannetti Elisa311ORCID,Peters Godefridus J.3ORCID

Affiliation:

1. Center for Oncological Research University of Antwerp Antwerp Belgium

2. Department of Pathology Antwerp University Hospital Antwerp Belgium

3. Laboratory of Medical Oncology Amsterdam Universities Medical Centers, VUmc Amsterdam The Netherlands

4. Experimental Pharmacology Laboratory IRCCS Istituto Tumori "Giovanni Paolo II" Bari Italy

5. Department of Pediatric Oncology/Hematology VUmc Amsterdam The Netherlands

6. Amsterdam University Medical Centers, VUmc Amsterdam The Netherlands

7. Division of Cancer, Department of Surgery & Cancer Imperial College London United Kingdom

8. Department of Clinical & Experimental Medicine, Faculty of Health & Medical Sciences University of Surrey Guildford United Kingdom

9. Pamgene International BV PamGene ‘s‐Hertogenbosch The Netherlands

10. Phase I‐Early Clinical Trials Unit, Oncology Department Antwerp University Hospital Antwerp Belgium

11. Cancer Pharmacology Lab, AIRC Start‐Up Unit Fondazione Pisana per la Scienza Pisa Italy

Funder

KWF Kankerbestrijding

Associazione Italiana per la Ricerca sul Cancro

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

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