LC‐HRMS‐based targeted metabolomics for high‐throughput and quantitative analysis of 21 growth inhibition‐related metabolites in Chinese hamster ovary cell fed‐batch cultures-Reference-Cited by-同舟云学术

LC‐HRMS‐based targeted metabolomics for high‐throughput and quantitative analysis of 21 growth inhibition‐related metabolites in Chinese hamster ovary cell fed‐batch cultures

Published:2022-02-08 Issue:5 Volume:36 Page:
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Lai Zijuan¹^ORCID,Choudhury Feroza K.¹,Tang Danming²,Liang Xiaorong¹,Dean Brian¹,Misaghi Shahram²,Sangaraju Dewakar¹

Affiliation:

1. Drug Metabolism and Pharmacokinetics Department Genentech Inc. South San Francisco California USA

2. Cell Culture and Bioprocess Operations Department Genentech Inc. South San Francisco California USA

Funder

Genentech

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.5348

Reference40 articles.

1. High resolution full scan liquid chromatography mass spectrometry comprehensive screening in sports antidoping urine analysis

2. Using Metabolomics to Identify Cell Line-Independent Indicators of Growth Inhibition for Chinese Hamster Ovary Cell-Based Bioprocesses

3. Toward Merging Untargeted and Targeted Methods in Mass Spectrometry-Based Metabolomics and Lipidomics

4. Metabolic signatures of GS-CHO cell clones associated with butyrate treatment and culture phase transition

5. Maximizing antibody production in a targeted integration host by optimization of subunit gene dosage and position

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