Elagolix Pharmacokinetic Profiles in Women With Renal or Hepatic Impairment
Author:
Affiliation:
1. Pharmaceutical DevelopmentAbbVie Inc. North Chicago IL USA
2. Orlando Clinical Research Center Orlando FL USA
3. BioanalysisAbbVie Inc. North Chicago IL USA
4. Clinical Pharmacology and PharmacometricsAbbVie Inc. North Chicago IL USA
Funder
AbbVie
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpdd.640
Reference13 articles.
1. Elagolix: First Global Approval
2. Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist
3. Elagolix treatment in women with heavy menstrual bleeding-associated with uterine fibroids: efficacy and safety results from a phase 2B study
4. Elagolix: a promising oral GnRH antagonist for endometriosis-associated pain
5. Dose-Dependent Suppression of Gonadotropins and Ovarian Hormones by Elagolix in Healthy Premenopausal Women
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1. Development and Application of a Physiologically Based Pharmacokinetic Model for Elagolix in the Adult and Adolescent Population;Clinical Pharmacokinetics;2024-07-26
2. Bioequivalence of Elagolix/Estradiol/Norethindrone Acetate Fixed‐Dose Combination Product: Phase 1 Results in Healthy Pre‐ and Postmenopausal Women;Clinical Pharmacology in Drug Development;2024-04-09
3. Comparing the pharmacokinetic and pharmacodynamic qualities of current and future therapies for uterine fibroids;Expert Opinion on Drug Metabolism & Toxicology;2022-08-03
4. Effects of elagolix on the pharmacokinetics of omeprazole and its metabolites in healthy premenopausal women;Clinical and Translational Science;2022-03-02
5. Population Pharmacokinetics of Elagolix in Combination with Low-Dose Estradiol/Norethindrone Acetate in Women with Uterine Fibroids;Clinical Pharmacokinetics;2021-12-08
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