Population Pharmacokinetics of Elagolix in Combination with Low-Dose Estradiol/Norethindrone Acetate in Women with Uterine Fibroids-Reference-Cited by-同舟云学术

Population Pharmacokinetics of Elagolix in Combination with Low-Dose Estradiol/Norethindrone Acetate in Women with Uterine Fibroids

Published:2021-12-08 Issue: Volume: Page:
ISSN:0312-5963
Container-title:Clinical Pharmacokinetics
language:en
Short-container-title:Clin Pharmacokinet

Author:

Beck Denise^ORCID,Winzenborg Insa^ORCID,Liu Mohan,Degner Jacob^ORCID,Mostafa Nael M.^ORCID,Noertersheuser Peter^ORCID,Shebley Mohamad^ORCID

Funder

AbbVie

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Link

https://link.springer.com/content/pdf/10.1007/s40262-021-01096-w.pdf

Reference13 articles.

1. Ng J, Chwalisz K, Carter DC, Klein CE. Dose-dependent suppression of gonadotropins and ovarian hormones by elagolix in healthy premenopausal women. J Clin Endocrinol Metab. 2017;102(5):1683–91.

2. Orilissa™ (elagolix) [United States package insert]. North Chicago: AbbVie Inc.; 2018.

3. Oriahnn™ (elagolix, estradiol, and norethindrone acetate capsules; elagolix capsules) [United States package insert]. North Chicago: AbbVie Inc.; 2020.

4. Barbieri RL. Hormone treatment of endometriosis: the estrogen threshold hypothesis. Am J Obstet Gynecol. 1992;166(2):740–5.

5. Surrey ES. Gonadotropin-releasing hormone agonist and add-back therapy: what do the data show? Curr Opin Obstet Gynecol. 2010;22(4):283–8.

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1. Bioequivalence of Elagolix/Estradiol/Norethindrone Acetate Fixed‐Dose Combination Product: Phase 1 Results in Healthy Pre‐ and Postmenopausal Women;Clinical Pharmacology in Drug Development;2024-04-09

2. GnRH agonists and antagonists in therapy of symptomatic uterine fibroids – current roles and future perspectives;Expert Opinion on Pharmacotherapy;2023-08-24

3. Interdisciplinary model‐informed drug development for extending duration of elagolix treatment in patients with uterine fibroids;British Journal of Clinical Pharmacology;2022-07-11