Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors-Reference-Cited by-同舟云学术

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

Published:2009-09 Issue:6‐7 Volume:1 Page:315-322
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Mendes‐Pereira Ana M.¹,Martin Sarah A.¹²,Brough Rachel¹²,McCarthy Afshan¹,Taylor Jessica R.¹,Kim Jung‐Sik³,Waldman Todd³,Lord Christopher J.¹,Ashworth Alan¹²

Affiliation:

1. The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK

2. CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK

3. Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, District of Columbia, USA

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/emmm.200900041

Reference30 articles.

1. A Synthetic Lethal Therapeutic Approach: Poly(ADP) Ribose Polymerase Inhibitors for the Treatment of Cancers Deficient in DNA Double-Strand Break Repair

2. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

3. Resistance to therapy caused by intragenic deletion in BRCA2

4. Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin

5. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

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