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Freeze-Drying of tert-Butanol/Water Cosolvent Systems: A Case Report on Formation of a Friable Freeze-Dried Powder of Tobramycin Sulfate

  • Published:2002-04 Issue:4 Volume:91 Page:1147-1155
  • ISSN:0022-3549
  • Container-title:Journal of Pharmaceutical Sciences
  • language:en
  • Short-container-title:Journal of Pharmaceutical Sciences

Author:

Wittaya-Areekul Sakchai,Needham Gregory F.,Milton Nathaniel,Roy Michael L.,Nail Steven L.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference15 articles.

1. Antimicrobial agents: The aminoglycosides;Sande,1995

2. Chemistry and conformation of aminoglycoside antibiotics: Tobramycin;Koch,1975

3. Solid state properties of tobramycin;Dash;Pharm Res,1991

4. The use of vancomycin and tobramycin in acrylic bone cement;Klekamp;J Arthroplasty,1999

5. Thermal analysis of the tertiary butyl alcohol–water system and its implications on freeze-drying;Kasraian;Pharm Res,1995

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