Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway-Reference-Cited by-同舟云学术

Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway

Published:2016-09-21 Issue:1 Volume:78 Page:37-48
ISSN:0272-4391
Container-title:Drug Development Research
language:en
Short-container-title:Drug Dev. Res.

Author:

Han Min Ho¹,Lee Dae-Sung¹,Jeong Jin-Woo²,Hong Su-Hyun³^ORCID,Choi Il-Whan⁴,Cha Hee-Jae⁵,Kim Suhkmann⁶,Kim Heui-Soo⁷,Park Cheol⁸,Kim Gi-Young⁹,Moon Sung-Kwon¹⁰,Kim Wun-Jae¹¹,Hyun Choi Yung³¹²

Affiliation:

1. Natural Products Research Team, Marine Biodiversity Institute of Korea; Seocheon 325-902 Republic of Korea

2. Anti-Aging Research Center & Blue-Bio Industry RIC, Dongeui University; Busan 614-714 Republic of Korea

3. Department of Biochemistry; Dongeui University College of Korean Medicine; Busan 614-052 Republic of Korea

4. Department of Microbiology; College of Medicine, Inje University; Busan 608-756 Republic of Korea

5. Departments of Parasitology and Genetics; College of Medicine, Kosin University; Busan 602-702 Republic of Korea

6. Department of Chemistry; College of Natural Sciences, Pusan National University; Busan 609-735 Republic of Korea

7. Department of Biological Sciences; College of Natural Sciences, Pusan National University; Busan 609-735 Republic of Korea

8. Department of Molecular Biology; College of Natural Sciences and Human Ecology, Dongeui University; Busan 614-714 Republic of Korea

9. Laboratory of Immunobiology, Department of Marine Life Sciences; Jeju National University; Jeju 690-756 Republic of Korea

10. School of Food Science and Technology; Chung-Ang University; Ansung 456-756 Republic of Korea

11. Department of Urology; College of Medicine and Institute for Tumor Research, Chungbuk National University; Cheongju 28644 Republic of Korea

Funder

Ministry of Oceans and Fisheries, and Ministry of Science, ICT and Future Planning, Korea

Publisher

Wiley

Subject

Drug Discovery

Reference58 articles.

1. Reactivation of telomerase in cancer;Akincilar;Cell Mol Life Sci,2016

2. Targeting the PI3K signaling pathway in cancer therapy;Bartholomeusz;Expert Opin Ther Targets,2012

3. Telomerase and other novel approaches to bladder cancer detection;Bennett;Clin Lab Sci,2008

4. Restoration of mitochondria function as a target for cancer therapy;Bhat;Drug Discov Today,2015

5. The anticancer effect of fucoidan in PC-3 prostate cancer cells;Boo;Mar Drugs,2013

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