COVID‐19 critical illness pathophysiology driven by diffuse pulmonary thrombi and pulmonary endothelial dysfunction responsive to thrombolysis

Author:

Poor Hooman D.1ORCID,Ventetuolo Corey E.2,Tolbert Thomas1,Chun Glen1,Serrao Gregory3,Zeidman Amanda4,Dangayach Neha S.5,Olin Jeffrey3,Kohli‐Seth Roopa6,Powell Charles A.1

Affiliation:

1. Division of Pulmonary, Critical Care, and Sleep MedicineIcahn School of Medicine at Mount Sinai New York New York USA

2. Department of Medicine and Health Services, Policy and PracticeAlpert Medical School of Brown University Providence Rhodes Island USA

3. Division of CardiologyIcahn School of Medicine at Mount Sinai New York New York USA

4. Division of NephrologyIcahn School of Medicine at Mount Sinai New York New York USA

5. Departments of Neurosurgery and NeurologyIcahn School of Medicine at Mount Sinai New York New York USA

6. Department of SurgeryIcahn School of Medicine at Mount Sinai New York New York USA

Funder

Foundation for the National Institutes of Health

Publisher

Wiley

Subject

Molecular Medicine,Medicine (miscellaneous)

Reference10 articles.

1. Covid‐19 does not lead to a “Typical” acute respiratory distress syndrome;Gattinoni L;Am J Respir Crit Care Med,2020

2. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy

3. KellyG AlexanderP CliffordM Pediatrica Intensiva Podcast 2.2 The Frontlines of COIVD19: Italian intensivists Gio Colombo & Lorenzo Grazioli 2 weeks into their enormous epidemic. 21 Mar 2020. Available from:http://pedsintensiva.libsyn.com/22-the-frontlines-of-covid19.

4. Portopulmonary hypertension and hepatopulmonary syndrome: a clinician‐oriented overview;Porres‐aguilar M;Eur Respir Rev,2012

5. Analysis of deaths during the severe acute respiratory syndrome (SARS) epidemic in Singapore: challenges in determining a SARS diagnosis;Chong PY;Arch Pathol Lab Med,2004

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