Analgesic and anti-inflammatory properties of novel, selective, and potent EP4 receptor antagonists-Reference-Cited by-同舟云学术

Analgesic and anti-inflammatory properties of novel, selective, and potent EP4 receptor antagonists

Published:2017-05-14 Issue:3 Volume:5 Page:e00316
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Chandrasekhar Srinivasan¹,Yu Xiao-Peng¹,Harvey Anita K.¹,Oskins Jennifer L.¹,Lin Chaohua¹,Wang Xushan¹,Blanco Maria-Jesus¹^ORCID,Fisher Matthew J.¹,Kuklish Steven L.¹,Schiffler Matthew A.¹,Vetman Tatiana¹,Warshawsky Alan M.¹,York Jeremy S.¹,Bendele Alison M.²,Chambers Mark G.¹^ORCID

Affiliation:

1. Lilly Research Laboratories; Eli Lilly and Company; Indianapolis Indiana 46285

2. Bolder BioPATH Inc.; Boulder Colorado 80309

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Reference45 articles.

1. Animal models of rheumatoid arthritis;Bendele;J Musculoskel Interact Neuronal Interact,2001

2. Development of a novel antibody to calcitonin gene-related peptide for the treatment of osteoarthritis-related pain;Benschop;Osteoarthritis and Cartilage,2014

3. a). Discovery of substituted-2, 4-dimethyl-(naphthalene-4-carbonyl) amino-benzoic acid as potent and selective EP4 antagonists;Blanco;Bioorg Med Chem Lett,2016a

4. b). Discovery of potent aryl-substituted 3-[(3-methylpyridine-2-carbonyl) amino]-2, 4-dimethyl-benzoic acid EP4 antagonists with improved pharmacokinetic profile;Blanco;Bioorg Med Chem Lett,2016b

5. c). Identification and biological activity of 6-alkyl-substituted 3-methylpyridine-2-carbonyl amino dimethyl-benzoic acid EP4 antagonists;Blanco;Bioorg Med Chem Lett,2016c

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