Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity-Reference-Cited by-同舟云学术

Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity

Published:2022-03-06 Issue:5 Volume:111 Page:1142-1154
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin Pharma and Therapeutics

Author:

Wegler Christine¹²,Wiśniewski Jacek R.³,Robertsen Ida⁴,Christensen Hege⁴,Kristoffer Hertel Jens⁵,Hjelmesæth Jøran⁵⁶,Jansson‐Löfmark Rasmus²,Åsberg Anders⁴⁷,Andersson Tommy B.²,Artursson Per¹

Affiliation:

1. Department of Pharmacy Uppsala University Uppsala Sweden

2. DMPK, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals Research and Development AstraZeneca Gothenburg Sweden

3. Biochemical Proteomics Group Department of Proteomics and Signal Transduction Max Planck Institute of Biochemistry Martinsried Germany

4. Department of Pharmacy Section for Pharmacology and Pharmaceutical Biosciences University of Oslo Oslo Norway

5. Morbid Obesity Centre Department of Medicine Vestfold Hospital Trust Tønsberg Norway

6. Department of Endocrinology, Morbid Obesity and Preventive Medicine Institute of Clinical Medicine University of Oslo Oslo Norway

7. Department of Transplantation Medicine Oslo University Hospital‐Rikshospitalet Oslo Norway

Funder

Vetenskapsrådet

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2558

Reference59 articles.

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2. Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling

3. Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients With a Wide Range of Body Weight

4. Proteomic Profiling of the Human Tissue and Biological Fluid Proteome

5. Protein Abundance of Clinically Relevant Drug-Metabolizing Enzymes in the Human Liver and Intestine: A Comparative Analysis in Paired Tissue Specimens

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