Synthesis of a 35S-labeled dinucleoside phosphorothioate prodrug, an orally bioavailable anti-HBV agent-Reference-Cited by-同舟云学术

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Synthesis of a 35S-labeled dinucleoside phosphorothioate prodrug, an orally bioavailable anti-HBV agent

Published:2012-05-03 Issue:6 Volume:55 Page:197-200
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J. Label Compd. Radiopharm

Author:

Rhee Sung-Whi¹,Iyer Radhakrishnan P.²,Coughlin John E.²,Padmanabhan Seetharamaiyer²,Malerich Jeremiah P.¹,Tanga Mary J.¹

Affiliation:

1. SRI International; 333 Ravenswood Avenue; Menlo Park; CA; 94025; USA

2. Spring Bank Pharmaceuticals, INC.; S-7, 113 Cedar Street; Milford; MA; 01757; USA

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jlcr.2925/fullpdf

Reference11 articles.

1. Hepatitis B. Fact sheet WHO/204 2000 http://www.who.int/inf-fs/en/fact204.htm

2. Phosphorothioate Di- and Trinucleotides as a Novel Class of Anti-Hepatitis B Virus Agents

3. Anti-Hepatitis B Virus Activity of ORI-9020, a Novel Phosphorothioate Dinucleotide, in a Transgenic Mouse Model

4. Orally bioavailable anti-HBV dinucleotide acyloxyalkyl prodrugs

5. R. P. Iyer et al Manuscript in preparation

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4. Assembly of Benzo[c][1,2]dithiol-3-ones via Acid-Promoted Denitrogenative Transannulation of Benzotriazinones;Organic Letters;2022-12-05

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