Distinguishing the optimal binding mechanism of an E3 ubiquitin ligase: Covalent versus noncovalent inhibition
Author:
Affiliation:
1. Molecular Bio‐Computation & Drug Design Lab, School of Health Sciences University of KwaZulu‐Natal Durban South Africa
2. Université Cadi Ayyad, Faculté des Sciences Semlalia, Département de Chimie Marrakech Morocco
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcb.28556
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1. Non-Covalent Interactions with Aromatic Rings: Current Understanding and Implications for Rational Drug Design
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3. Optimized Hydrophobic Interactions and Hydrogen Bonding at the Target-Ligand Interface Leads the Pathways of Drug-Designing
4. Noncovalent interaction-assisted drug delivery system with highly efficient uptake and release of paclitaxel for anticancer therapy
5. Role of non-covalent and covalent interactions in cargo loading capacity and stability of polymeric micelles
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