Predicting transporter-mediated drug interactions: Commentary on: “Pharmacokinetic evaluation of a drug transporter cocktail consisting of digoxin, furosemide, metformin and rosuvastatin” and “Validation of a microdose probe drug cocktail for clinical dru-Reference-Cited by-同舟云学术

Predicting transporter-mediated drug interactions: Commentary on: “Pharmacokinetic evaluation of a drug transporter cocktail consisting of digoxin, furosemide, metformin and rosuvastatin” and “Validation of a microdose probe drug cocktail for clinical dru

Published:2017-02-18 Issue:4 Volume:101 Page:447-449
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Zhang L¹,Sparreboom A²

Affiliation:

1. Office of Clinical Pharmacology; Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration; Silver Spring Maryland USA

2. Division of Pharmaceutics and Pharmaceutical Chemistry; College of Pharmacy and Comprehensive Cancer Center, Ohio State University; Columbus Ohio USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpt.588/fullpdf

Reference8 articles.

1. Membrane transporters in drug development;International Transporter Consortium;Nat. Rev. Drug. Discov.,2010

2. U.S. Food and Drug Administration Guidance for Industry: Drug Interaction Studies - Study Design, Data Analysis, Implications for Dosing, and Labeling Recommendations http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm064982.htm 2012

3. Cocktail” approaches and strategies in drug development: valuable tool or flawed science?;Zhou;J. Clin. Pharmacol.,2004

4. Evaluation of proposed in vivo probe substrates and inhibitors for phenotyping transporter activity in humans;Momper;J. Clin. Pharmacol.,2016

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