Parametric and Nonparametric Methods in Population Pharmacokinetics: Experts’ Discussion on Use, Strengths, and Limitations

Author:

Goutelle Sylvain123ORCID,Woillard Jean‐Baptiste456,Buclin Thierry7,Bourguignon Laurent123,Yamada Walter89,Csajka Chantal1011,Neely Michael89,Guidi Monia710ORCID

Affiliation:

1. Hospices Civils de Lyon Groupement Hospitalier Nord Service de Pharmacie Lyon France

2. CNRS, UMR 5558 Laboratoire de Biométrie et Biologie Évolutive Villeurbanne France

3. Univ Lyon Université Claude Bernard Lyon 1 ISPB—Faculté de Pharmacie de Lyon Lyon France

4. Univ. Limoges IPPRITT Limoges France

5. INSERM IPPRITT, U1248 Limoges France

6. Department of Pharmacology and Toxicology, CHU Limoges Limoges France

7. Service of Clinical Pharmacology Lausanne University Hospital and University of Lausanne Lausanne Switzerland

8. Keck School of Medicine University of Southern California Los Angeles California USA

9. Laboratory of Applied Pharmacokinetics and Bioinformatics at the Saban Research Institute Children's Hospital Los Angeles Los Angeles California USA

10. Center for Research and Innovation in Clinical Pharmaceutical Sciences Lausanne University Hospital and University of Lausanne Lausanne Switzerland

11. Institute of Pharmaceutical Sciences of Western Switzerland University of Geneva University of Lausanne, Geneva Lausanne Switzerland

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference58 articles.

1. Parametric approaches in population pharmacokinetics;Guidi M;J Clin Pharmacol,2022

2. Nonparametric methods in population harmacokinetics;Goutelle S;J Clin Pharmacol,2022

3. Mixed Effects Models for the Population Approach

4. A Population Pharmacokinetic Analysis of Continuous Infusion of Cloxacillin during Staphylococcus aureus Bone and Joint Infections

5. Handling covariates in population pharmacokinetics

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