Safety, Pharmacokinetic, Immunogenicity, and Pharmacodynamic Responses in Healthy Volunteers Following a Single Intravenous Injection of Purified Staphylococcal Protein A-Reference-Cited by-同舟云学术

Safety, Pharmacokinetic, Immunogenicity, and Pharmacodynamic Responses in Healthy Volunteers Following a Single Intravenous Injection of Purified Staphylococcal Protein A

Published:2013-07-07 Issue:9 Volume:53 Page:909-918
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Ballow Charles¹,Leh Anissa²,Slentz-Kesler Kimberly³,Yan Jim³,Haughey David⁴,Bernton Edward²

Affiliation:

1. Buffalo Clinical Research Center; Buffalo NY USA

2. Protalex, Inc.; Summit NJ USA

3. Almac Diagnostics, LLC; Durham NC USA

4. Icon PLC, Inc.; Whitesboro NY USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcph.119/fullpdf

Reference23 articles.

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2. Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity;Graille;Proc Natl Acad Sci USA.,2000

3. 2012

4. Temporal and dose-dependent relationships between in vivo B cell receptor-targeted proliferation and deletion-induced by a microbial B cell toxin;Goodyear;J Immunol.,2006

5. Mechanism of activation of human basophils by Staphylococcus aureus Cowan 1;Marone;Infect Immunol.,1987

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