Safety Assessment of Protein A and Derivation of a Parenteral Health-Based Exposure Limit

Author:

Graham JessicaORCID,Anand Sathanandam S.,Bercu Joel,Besenhofer Lauren,de Zafra Christina,Feng Yu,Fisher Craig,Hillegass Jedd,Hutchinson Richard,Jolly Robert,Moudgal Chandrika,Nicholas Tyler,Olszova Daniela,Schmitz Matthew,Semmelmann Florian

Publisher

Elsevier BV

Reference53 articles.

1. 21 CFR Part 610.13, U.S. Code of Federal Regulations Title 21 Food and Drugs - Part 610.13 Purity.

2. ASTM, 2020. E3219−20: Standard Guide for the Derivation of Health Based Exposure Limits (HBELs). West Conshohocken, PA.

3. Safety, pharmacokinetic, immunogenicity, and pharmacodynamic responses in healthy volunteers following a single intravenous injection of purified staphylococcal protein A;Ballow;The Journal of Clinical Pharmacology,2013

4. Application of the threshold of toxicological concern concept when applied to pharmaceutical manufacturing operations intended for short-term clinical trials;Bercu;Regul Toxicol Pharmacol,2013

5. Potential impurities in drug substances: Compound-specific toxicology limits for 20 synthetic reagents and by-products, and a class-specific toxicology limit for alkyl bromides;Bercu;Regul Toxicol Pharmacol,2018

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3