Application of 2D EXSY and qNMR Spectroscopy for Diastereomeric Excess Determination Following Chiral Resolution of β‐Lactams-Reference-Cited by-同舟云学术

Application of 2D EXSY and qNMR Spectroscopy for Diastereomeric Excess Determination Following Chiral Resolution of β‐Lactams

Published:2022-07-25 Issue: Volume: Page:
ISSN:2191-1363
Container-title:ChemistryOpen
language:en
Short-container-title:ChemistryOpen

Author:

McLoughlin Eavan C.¹^ORCID,O'Brien John E.²,Trujillo Cristina³^ORCID,Meegan Mary J.¹^ORCID,O'Boyle Niamh M.¹^ORCID

Affiliation:

1. School of Pharmacy and Pharmaceutical Sciences Panoz Institute and Trinity Biomedical Sciences Institute 152-160 Pearse Street Trinity College Dublin Dublin 2 Ireland

2. School of Chemistry Trinity College Dublin Dublin 2 Ireland

3. Trinity Biomedical Sciences Institute School of Chemistry Trinity College Dublin Dublin 2 Ireland

Funder

Wellcome Trust

Publisher

Wiley

Subject

General Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/open.202200119

Reference58 articles.

2. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β -lactam bridged combretastatin A-4 analogues as potent antitumor agents

3. Potent Antitumor Activities and Structure Basis of the Chiral β-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin

5. Synthesis and Antiproliferative Evaluation of 3-Chloroazetidin-2-ones with Antimitotic Activity: Heterocyclic Bridged Analogues of Combretastatin A-4

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