Development of a Practical Synthesis of 4′-Azido-2′β-Methyl-2′-Desoxycytosine and Its Prodrugs as HCV Chemotherapeutic Agents
Author:
Affiliation:
1. Janssen Pharmaceutica; Pharmaceutical Development and Manufacturing Sciences; Turnhoutseweg 30 B-2340 Beerse Belgium
Publisher
Wiley-VCH Verlag GmbH & Co. KGaA
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/9783527801756.ch7/fullpdf
Reference44 articles.
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2. Synthesis of new 2′-deoxy-2′-fluoro-4′-azido nucleoside analogues as potent anti-HIV agents;Wang;Eur. J. Med. Chem.,2011
3. 2′-Deoxy-4′-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2′-alpha-hydroxyl groups;Klumpp;J. Biol. Chem.,2008
4. The design, synthesis, and antiviral activity of 4′-azidocytidine analogues against hepatitis C virus replication: the discovery of 4′-azidoarabinocytidine;Smith;J. Med. Chem.,2009
5. The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4′-azidocytidine against hepatitis C virus replication: the discovery of 4′-azido-2′-deoxy-2′-fluorocytidine and 4′-azido-2′-dideoxy-2′,2′-difluorocytidine;Smith;J. Med. Chem.,2009
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