Association of Retromer Deficiency and Tau Pathology in Down Syndrome
Author:
Affiliation:
1. Alzheimer's Center at Temple Temple University Lewis Katz School of Medicine Philadelphia PA
2. Department of Clinical Sciences Temple University Lewis Katz School of Medicine Philadelphia PA
Funder
National Institute on Aging
Publisher
Wiley
Subject
Neurology (clinical),Neurology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ana.26321
Reference24 articles.
1. Endosomal sorting and trafficking, the retromer complex and neurodegeneration
2. Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
3. VPS35 regulates tau phosphorylation and neuropathology in tauopathy
4. Vps35 Deficiency Impairs Cdk5/p35 Degradation and Promotes the Hyperphosphorylation of Tau Protein in Retinal Ganglion Cells
5. Retromer regulates the lysosomal clearance of MAPT/tau
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