Dysfunction of the retromer complex system contributes to amyloid and tau pathology in a stem cell model of Down syndrome
Author:
Affiliation:
1. Alzheimer's Center at Temple Lewis Katz School of Medicine Temple University Philadelphia Pennsylvania USA
2. School of Pharmacy Temple University Philadelphia Pennsylvania USA
Funder
National Institutes of Health
Publisher
Wiley
Subject
Psychiatry and Mental health,Neurology (clinical)
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/trc2.12334
Reference29 articles.
1. Further understanding the connection between Alzheimer's disease and Down syndrome
2. A prospective 20-year longitudinal follow-up of dementia in persons with Down syndrome
3. A prospective 14-year longitudinal follow-up of dementia in persons with Down syndrome
4. A Prospective Study of Alzheimer Disease in Down Syndrome
5. Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years
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1. Retromer Stabilization Improves Cognitive Function and Synaptic Plasticity in a Mouse Model of Down Syndrome;Journal of Alzheimer's Disease;2023-07-18
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3. Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact ofAPPDose and Preclinical Studies of a γ‐Secretase Modulator;Annals of Neurology;2023-04-29
4. State‐of‐the‐art therapy for Down syndrome;Developmental Medicine & Child Neurology;2023-01-24
5. Realizing the potential of exploiting human IPSCs and their derivatives in research of Down syndrome;BIOCELL;2023
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