A New Workflow for Whole-Genome Sequencing of Single Human Cells

Author:

Binder Vera1,Bartenhagen Christoph2,Okpanyi Vera1,Gombert Michael1,Moehlendick Birte3,Behrens Bianca3,Klein Hans-Ulrich2,Rieder Harald4,Ida Krell Pina Fanny1,Dugas Martin2,Stoecklein Nikolas Hendrik3,Borkhardt Arndt1

Affiliation:

1. Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty; University of Duesseldorf; Duesseldorf Germany

2. Institute of Medical Informatics; University of Muenster; Muenster Germany

3. Department of General, Visceral and Pediatric Surgery, Medical Faculty; University of Duesseldorf; Duesseldorf Germany

4. Institute of Human Genetics and Anthropology; University of Duesseldorf; Duesseldorf Germany

Funder

Deutsche Forschungsgemeinschaft

Krebsgesellschaft NRW

Publisher

Wiley

Subject

Genetics(clinical),Genetics

Reference40 articles.

1. A map of human genome variation from population-scale sequencing;Abecasis;Nature,2010

2. Affymetrix 2008 A ffymetrix W hite P aper: the loss of heterozygosity algorithm in genotyping console 2.0 http://media.affymetrix.com/support/technical/whitepapers/loh_algorithm_gtc2_whitepaper.pdf

3. Genetic variegation of clonal architecture and propagating cells in leukaemia;Anderson;Nature,2011

4. Dissecting genomic diversity, one cell at a time;Blainey;Nat Methods,2014

5. Control-free calling of copy number alterations in deep-sequencing data using GC-content normalization;Boeva;Bioinformatics,2011

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