Dopaminergic Positron Emission Tomography Imaging in the Alpha‐Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease-Reference-Cited by-同舟云学术

Dopaminergic Positron Emission Tomography Imaging in the Alpha‐Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease

Published:2022-05-07 Issue:8 Volume:37 Page:1739-1748
ISSN:0885-3185
Container-title:Movement Disorders
language:en
Short-container-title:Movement Disorders

Author:

Sossi Vesna¹,Patterson Joseph R.²,McCormick Siobhan³,Kemp Christopher J.²,Miller Kathryn M.²,Stoll Anna C.²,Kuhn Nathan²,Kubik Michael²,Kochmanski Joseph²,Luk Kelvin C.⁴,Sortwell Caryl E.²^ORCID

Affiliation:

1. Department of Physics and Astronomy University of British Columbia Vancouver British Columbia Canada

2. Department of Translational Neuroscience Michigan State University Grand Rapids Michigan USA

3. Pacific Parkinson's Research Centre University of British Columbia Vancouver British Columbia Canada

4. Department of Pathology and Laboratory Medicine University of Pennsylvania Philadelphia Pennsylvania USA

Funder

National Institute of Neurological Disorders and Stroke

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/mds.29051

Reference35 articles.

1. Increase in Dopamine Turnover Occurs Early in Parkinson's Disease: Evidence from a New Modeling Approach to PET 18F-Fluorodopa Data

2. Dopamine turnover increases in asymptomatic LRRK2 mutations carriers

3. PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation

4. In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease

5. Rate of progression in Parkinson's disease: A 6-[18F]fluoro-L-dopa PET study

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3. Dopaminergic neuron loss in mice due to increased levels of wild-type human α-Synuclein only takes place under conditions of accelerated aging;Scientific Reports;2024-01-30

4. Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils;npj Parkinson's Disease;2024-01-03

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