Regulation of adipose tissue inflammation and systemic metabolism in murine obesity by polymer implants loaded with lentiviral vectors encoding human interleukin‐4-Reference-Cited by-同舟云学术

Regulation of adipose tissue inflammation and systemic metabolism in murine obesity by polymer implants loaded with lentiviral vectors encoding human interleukin‐4

Published:2020-08-18 Issue:12 Volume:117 Page:3891-3901
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnology and Bioengineering

Author:

Youngblood Richard¹,Flesher Carmen G.²,Delproposto Jennifer³,Baker Nicki A.²,Neeley Christopher K.²,Li Fanghua¹,Lumeng Carey N.³⁴⁵,Shea Lonnie D.¹^ORCID,O'Rourke Robert W.²⁶^ORCID

Affiliation:

1. Department of Biomedical Engineering University of Michigan Ann Arbor Michigan

2. Department of Surgery University of Michigan Medical School Ann Arbor Michigan

3. Department of Pediatrics and Communicable Diseases University of Michigan Medical School Ann Arbor Michigan

4. Graduate Program in Immunology, Veterans Affairs Ann Arbor Healthcare System Ann Arbor Michigan

5. Graduate Program in Cellular and Molecular Biology, Veterans Affairs Ann Arbor Healthcare System Ann Arbor Michigan

6. Department of Surgery Veterans Affairs Ann Arbor Healthcare System Ann Arbor Michigan

Funder

Center for Scientific Review

Center for Integrated Healthcare, U.S. Department of Veterans Affairs

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.27523

Reference40 articles.

1. Anti-inflammatory effect of exercise training in subjects with type 2 diabetes and the metabolic syndrome is dependent on exercise modalities and independent of weight loss

2. Gene transfer with IL-4 and IL-13 improves survival in lethal endotoxemia in the mouse and ameliorates peritoneal macrophages immune competence

3. A PLG/HAp composite scaffold for lentivirus delivery

4. An MHC II-Dependent Activation Loop between Adipose Tissue Macrophages and CD4+ T Cells Controls Obesity-Induced Inflammation

5. Interleukin-10 is a protective factor against diet-induced insulin resistance in liver

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