High cysteine concentrations in cell culture media lead to oxidative stress and reduced bioprocess performance of recombinant CHO cells-Reference-Cited by-同舟云学术

High cysteine concentrations in cell culture media lead to oxidative stress and reduced bioprocess performance of recombinant CHO cells

Author:

Komuczki Daniel¹²,Stadermann Anna³,Bentele Maximilian²,Unsoeld Andreas⁴,Grillari Johannes⁵⁶,Mueller Markus M.²,Paul Albert²,Fischer Simon³^ORCID

Affiliation:

1. Institute of Bioprocess Sciences and Engineering (IBSE) University of Natural Resources and Life Sciences Vienna Austria

2. Upstream Development, Bioprocess and Analytical Development Boehringer Ingelheim Pharma GmbH & Co.KG Biberach a. d. Riss Germany

3. Cell Line Development, Bioprocess Development Biologicals Boehringer Ingelheim Pharma GmbH & Co.KG Biberach a. d. Riss Germany

4. Cell Culture Media Development, Bioprocess Development Biologicals Boehringer Ingelheim Pharma GmbH & Co.KG Biberach a. d. Riss Germany

5. Institute of Molecular Biotechnology University of Natural Resources and Life Sciences Vienna Austria

6. Ludwig Boltzmann Institute for Traumatology. The Research Center in Cooperation with AUVA Vienna Austria

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Link

Reference59 articles.

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