Modulating tyrosine sulfation of recombinant antibodies in CHO cell culture by host selection and sodium chlorate supplementation
Author:
Affiliation:
1. Process Cell Sciences Merck & Co., Inc. Kenilworth New Jersey USA
Publisher
Wiley
Subject
Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.202100142
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1. Assessing monoclonal antibody product quality attribute criticality through clinical studies
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4. In vitro and in vivo modifications of recombinant and human IgG antibodies
5. Processing of C-terminal lysine and arginine residues of proteins isolated from mammalian cell culture
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