Subcloning induces changes in the DNA‐methylation pattern of outgrowing Chinese hamster ovary cell colonies

Author:

Weinguny Marcus12,Klanert Gerald1,Eisenhut Peter12,Lee Isac3,Timp Winston3,Borth Nicole12ORCID

Affiliation:

1. ACIB Gmbh Austrian Centre of Industrial Biotechnology Vienna Austria

2. Department of Biotechnology University of Natural Resources and Life Sciences, Vienna Vienna Austria

3. Department of Biomedical Engineering Johns Hopkins University Baltimore USA

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Reference67 articles.

1. Dynamics and context‐dependent roles of DNA methylation;Ambrosi C.;Journal of Molecular Biology, Molecular Mechanisms of Stem Cells Pluripotency and Cell Fate Specification,2017

2. HTSeq--a Python framework to work with high-throughput sequencing data

3. Recurring genomic structural variation leads to clonal instability and loss of productivity

4. Regulation of chromatin by histone modifications

5. Stability of protein production from recombinant mammalian cells

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