Alanyl‐tRNA synthetase AARS1: A novel lactate sensor and lactyltransferase mediating p53 lactylation and tumorigenesis-Reference-Cited by-同舟云学术

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Alanyl‐tRNA synthetase AARS1: A novel lactate sensor and lactyltransferase mediating p53 lactylation and tumorigenesis

Published:2024-07-24 Issue:3 Volume:3 Page:
ISSN:2769-6448
Container-title:MedComm – Oncology
language:en
Short-container-title:MedComm – Oncology

Author:

Yang Qiqing¹²,Li Heyu¹²,Zhang Long¹²³^ORCID

Affiliation:

1. Life Sciences Institute, The Second Affiliated Hospital of Zhejiang University School of Medicine Zhejiang University Hangzhou China

2. The MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, The First Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang China

3. Cancer Center Zhejiang University Hangzhou Zhejiang China

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/mog2.83

Reference5 articles.

1. Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis

2. Metabolic regulation of gene expression by histone lactylation

3. YiaC and CobB regulate lysine lactylation in Escherichia coli

4. Metabolic regulation of homologous recombination repair by MRE11 lactylation

5. Phase separation of p53 induced by its unstructured basic region and prevented by oncogenic mutations in tetramerization domain

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