Phase separation of p53 induced by its unstructured basic region and prevented by oncogenic mutations in tetramerization domain-Reference-Cited by-同舟云学术

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Phase separation of p53 induced by its unstructured basic region and prevented by oncogenic mutations in tetramerization domain

Published:2022-12 Issue: Volume:222 Page:207-216
ISSN:0141-8130
Container-title:International Journal of Biological Macromolecules
language:en
Short-container-title:International Journal of Biological Macromolecules

Author:

Chen Chen,Fu Gaohong,Guo Quanqiang,Xue Song,Luo Shi-Zhong

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Molecular Biology,General Medicine,Biochemistry,Structural Biology

Reference66 articles.

1. Biomolecular condensates: organizers of cellular biochemistry;Banani;Nat. Rev. Mol. Cell Biol.,2017

2. Protein phase separation: a new phase in cell biology;Boeynaems;Trends Cell Biol.,2018

3. Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases;Zhang;Sci. China Life Sci.,2020

4. Aberrant phase transitions: side effects and novel therapeutic strategies in human disease;Verdile;Front. Genet.,2019

5. Combating deleterious phase transitions in neurodegenerative disease;Darling;Biochim. Biophys. Acta, Mol. Cell Res.,2021

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1. The role of liquid-liquid phase separation in defining cancer EMT;Life Sciences;2024-09

2. Alanyl‐tRNA synthetase AARS1: A novel lactate sensor and lactyltransferase mediating p53 lactylation and tumorigenesis;MedComm – Oncology;2024-07-24

3. Screening of liquid–liquid phase separation conditions for proteins with a mixed solution kit of biomacromolecular crowding agents;Journal of Molecular Liquids;2024-07

4. Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis;Cell;2024-05

5. Interplay between posttranslational modifications and liquid‒liquid phase separation in tumors;Cancer Letters;2024-03

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