The Brain Chart of Aging: Machine‐learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans-Reference-Cited by-同舟云学术

The Brain Chart of Aging: Machine‐learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans

Published:2020-09-13 Issue:1 Volume:17 Page:89-102
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Habes Mohamad¹²³⁴^ORCID,Pomponio Raymond¹⁴,Shou Haochang¹⁵,Doshi Jimit¹⁴,Mamourian Elizabeth¹⁴,Erus Guray¹⁴,Nasrallah Ilya¹⁴,Launer Lenore J.⁶,Rashid Tanweer¹⁴,Bilgel Murat⁷,Fan Yong¹⁴,Toledo Jon B.⁸⁹,Yaffe Kristine¹⁰,Sotiras Aristeidis¹¹¹,Srinivasan Dhivya¹⁴,Espeland Mark¹²,Masters Colin¹³,Maruff Paul¹³,Fripp Jurgen¹⁴,Völzk Henry¹⁵,Johnson Sterling C.¹⁶,Morris John C.¹⁷,Albert Marilyn S.¹⁸,Miller Michael I.¹⁹,Bryan R. Nick²⁰,Grabe Hans J.²¹²²,Resnick Susan M.⁷,Wolk David A.¹²,Davatzikos Christos¹⁴,

Affiliation:

1. Center for Biomedical Image Computing and Analytics University of Pennsylvania Philadelphia Pennsylvania USA

2. Department of Neurology and Penn Memory Center University of Pennsylvania Philadelphia Pennsylvania USA

3. Neuroimage Analytics Laboratory and Biggs Institute Neuroimaging Core Glenn Biggs Institute for Neurodegenerative Disorders University of Texas Health Science Center at San Antonio San Antonio Texas USA

4. Department of Radiology University of Pennsylvania Philadelphia Pennsylvania USA

5. Department of Biostatistics Epidemiology and Informatics University of Pennsylvania Philadelphia Pennsylvania USA

6. Laboratory of Epidemiology and Population Sciences National Institute on Aging Bethesda Maryland USA

7. Laboratory of Behavioral Neuroscience National Institute on Aging Baltimore Maryland USA

8. Department of Pathology and Laboratory Medicine Institute on Aging Center for Neurodegenerative Disease Research University of Pennsylvania School of Medicine Philadelphia Pennsylvania USA

9. Stanley Appel Department of Neurology Houston Methodist Hospital Houston Texas USA

10. Departments of Neurology Psychiatry and Epidemiology and Biostatistics University of California San Francisco San Francisco California USA

11. Department of Radiology Washington University in St. Louis St. Louis Missouri USA

12. Department of Biostatistics and Data Science Wake Forest School of Medicine Winston‐Salem North Carolina USA

13. Florey Institute of Neuroscience and Mental Health University of Melbourne Melbourne Australia

14. CSIRO Health and Biosecurity Australian e‐Health Research Centre CSIRO Australia

15. Institute for Community Medicine University of Greifswald Greifswald Germany

16. Wisconsin Alzheimer's Institute University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA

17. Department of Neurology Washington University in St. Louis St. Louis Missouri USA

18. Department of Neurology Johns Hopkins University School of Medicine Baltimore Maryland USA

19. Department of Biomedical Engineering Johns Hopkins University Baltimore Maryland USA

20. Department of Diagnostic Medicine University of Texas Austin Texas USA

21. Department of Psychiatry and Psychotherapy University of Greifswald Germany

22. German Center for Neurodegenerative Diseases (DZNE) Rostock Greifswald Germany

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12178

Reference44 articles.

1. White matter hyperintensities and imaging patterns of brain ageing in the general population

2. Longitudinal Magnetic Resonance Imaging Studies of Older Adults: A Shrinking Brain

3. Trajectories of brain aging in middle-aged and older adults: Regional and individual differences

4. Age-Based Comparison of Human Dendritic Spine Structure Using Complete Three-Dimensional Reconstructions

5. Advanced brain aging: relationship with epidemiologic and genetic risk factors, and overlap with Alzheimer disease atrophy patterns

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