Brain aging patterns in a large and diverse cohort of 49,482 individuals
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Published:2024-08-15
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ISSN:1078-8956
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Container-title:Nature Medicine
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language:en
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Short-container-title:Nat Med
Author:
Yang ZhijianORCID, Wen JunhaoORCID, Erus GurayORCID, Govindarajan Sindhuja T., Melhem Randa, Mamourian ElizabethORCID, Cui Yuhan, Srinivasan Dhivya, Abdulkadir Ahmed, Parmpi Paraskevi, Wittfeld KatharinaORCID, Grabe Hans J., Bülow Robin, Frenzel Stefan, Tosun DuyguORCID, Bilgel MuratORCID, An Yang, Yi DahyunORCID, Marcus Daniel S., LaMontagne PamelaORCID, Benzinger Tammie L. S.ORCID, Heckbert Susan R.ORCID, Austin Thomas R., Waldstein Shari R., Evans Michele K., Zonderman Alan B., Launer Lenore J.ORCID, Sotiras AristeidisORCID, Espeland Mark A., Masters Colin L., Maruff PaulORCID, Fripp Jurgen, Toga Arthur W., O’Bryant Sid, Chakravarty Mallar M.ORCID, Villeneuve SylviaORCID, Johnson Sterling C.ORCID, Morris John C., Albert Marilyn S., Yaffe Kristine, Völzke Henry, Ferrucci LuigiORCID, Nick Bryan R., Shinohara Russell T., Fan YongORCID, Habes MohamadORCID, Lalousis Paris Alexandros, Koutsouleris NikolaosORCID, Wolk David A., Resnick Susan M.ORCID, Shou HaochangORCID, Nasrallah Ilya M.ORCID, Davatzikos ChristosORCID
Funder
U.S. Department of Health & Human Services | NIH | National Institute on Aging
Publisher
Springer Science and Business Media LLC
Reference102 articles.
1. Peters, R. Ageing and the brain. Postgrad. Med J. 82, 84–88 (2006). 2. Davatzikos, C., Xu, F., An, Y., Fan, Y. & Resnick, S. M. Longitudinal progression of Alzheimer’s-like patterns of atrophy in normal older adults: the SPARE-AD index. Brain 132, 2026–2035 (2009). 3. Dubois, B. et al. Preclinical Alzheimer’s disease: definition, natural history, and diagnostic criteria. Alzheimers Dement. 12, 292–323 (2016). 4. Davatzikos, C. Machine learning in neuroimaging: progress and challenges. Neuroimage 197, 652–656 (2019). 5. Tian, Y. E. et al. Heterogeneous aging across multiple organ systems and prediction of chronic disease and mortality. Nat. Med. 29, 1221–1231 (2023).
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