Interleukin-6 increases expression of serine protease inhibitor Kazal type 1 through STAT3 in colorectal adenocarcinoma

Author:

Räsänen Kati1,Lehtinen Elina1,Nokelainen Kristiina1,Kuopio Teijo23,Hautala Laura1,Itkonen Outi4,Stenman Ulf-Håkan1,Koistinen Hannu1

Affiliation:

1. Department of Clinical Chemistry; Medicum; University of Helsinki; Helsinki Finland

2. Department of Pathology; Central Finland Central Hospital; Jyväskylä Finland

3. Department of Biological and Environmental Science; Division of Cell and Molecular Biology; University of Jyväskylä; Jyväskylä Finland

4. HUSLAB; Helsinki University Central Hospital; Helsinki Finland

Funder

Suomen Akatemia

Sigrid Jusélius Foundation

Finska Läkaresällskapet

Helsinki University Central Hospital Research Fund

Orion Research Foundation

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference55 articles.

1. http://globocan.iarc.fr/old/FactSheets/cancers/colorectal-new.asp

2. Colorectal cancer: How emerging molecular understanding affects treatment decisions;Sridharan;Oncology (Williston Park),2014

3. Inflammation and colon cancer;Terzic;Gastroenterology,2010

4. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer;Taniguchi;Semin Immunol,2014

5. Interleukin-6-A key regulator of colorectal cancer development;Waldner;Int J Biol Sci,2012

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