Drug metabolite identification using ultrahigh‐performance liquid chromatography–ultraviolet spectroscopy and parallelized scans on a tribrid Orbitrap mass spectrometer
Author:
Affiliation:
1. DMPK/ADME Research and Early Development, Oncology R&DAstraZeneca Cambridge UK
Publisher
Wiley
Subject
Organic Chemistry,Spectroscopy,Analytical Chemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/rcm.8735
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4. Studies on cytochrome P‐450‐mediated bioactivation of diclofenac in rats and in human hepatocytes: Identification of glutathione conjugated metabolites;Tang W;Drug Metab Dispos,1999
5. Rapid screening and characterization of glutathione-trapped reactive metabolites using a polarity switch-based approach on a high-resolution quadrupole orbitrap mass spectrometer
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