Predictions of genotoxic potential, mode of action, molecular targets, and potencyviaa tiered multiflow® assay data analysis strategy
Author:
Affiliation:
1. Litron Laboratories; Rochester New York
2. Merck & Co., Inc.; West Point Pennsylvania
3. Institute of Life Science, Swansea University Medical School; Swansea University; Swansea Wales United Kingdom
Funder
National Institute of Health/National Institute of Environmental Health Sciences
Publisher
Wiley
Subject
Health, Toxicology and Mutagenesis,Genetics (clinical),Epidemiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/em.22274/fullpdf
Reference97 articles.
1. Molecular cytogenetic evaluation of the mechanism of micronucleus formation induced by camptothecin, topotecan, and irinotecan;Attia;Environ Mol Mutagen,2009
2. In vitro micronucleus scoring by flow cytometry: differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability;Avlasevich;Environ Mol Mutagen,2006
3. ALK inhibitors in non-small cell lung cancer: crizotinib and beyond;Awad;Clin Adv Hematol Oncol,2014
4. Genotoxicity of two anticancer drugs, gemcitabine and topotecan, in mouse bone marrow in vivo;Aydemir;Mutat Res,2003
5. Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data;Bemis;Mutagenesis,2016
Cited by 26 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology;Mutagenesis;2023-06-10
2. Quantitative interpretation of ToxTracker dose–response data for potency comparisons and mode‐of‐action determination;Environmental and Molecular Mutagenesis;2023-02
3. Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose;Environmental and Molecular Mutagenesis;2022-12-22
4. A new imaging platform ( iScreen ) allows for the concurrent assessment of micronucleus induction and genotoxic mode of action in human A375 cells;Environmental and Molecular Mutagenesis;2022-06
5. Science‐Based Approach to Harmonize Contraception Recommendations in Clinical Trials and Pharmaceutical Labels;Clinical Pharmacology & Therapeutics;2022-05-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3