Developing a Bayesian adaptive design for a phase I clinical trial: a case study for a novel HIV treatment-Reference-Cited by-同舟云学术

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Developing a Bayesian adaptive design for a phase I clinical trial: a case study for a novel HIV treatment

Published:2016-11-27 Issue:5 Volume:36 Page:754-771
ISSN:0277-6715
Container-title:Statistics in Medicine
language:en
Short-container-title:Statist. Med.

Author:

Mason Alexina J.¹,Gonzalez-Maffe Juan²,Quinn Killian³,Doyle Nicki³,Legg Ken³,Norsworthy Peter³,Trevelion Roy⁴,Winston Alan³,Ashby Deborah²^ORCID

Affiliation:

1. Department of Health Services Research and Policy; London School of Hygiene and Tropical Medicine; 15-17 Tavistock Place London WC1H 9SH U.K.

2. Imperial Clinical Trials Unit; Imperial College London; 68 Wood Lane London W12 7RH U.K.

3. Section of Infectious Diseases, Department of Medicine; Imperial College London; London W2 1PG U.K.

4. HIV i-Base

Funder

Medical Research Council and the National Institute for Health Research (NIHR)

Centro de Investigación Biomédica en Red de Salud Mental

Publisher

Wiley

Subject

Statistics and Probability,Epidemiology

Reference26 articles.

1. Design and analysis of phase I clinical trials;Storer;Biometrics,1989

2. Dose escalation methods in phase I cancer clinical trials;Le Tourneau;Journal of the National Cancer Institute,2009

3. Continual reassessment method: a practical design for phase 1 clinical trials in cancer;O'Quigley;Biometrics,1990

4. A comparison of two phase I trial designs;Korn;Statistics in Medicine,1994

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