Pharmacokinetics of Asfotase Alfa in Adult Patients With Pediatric‐Onset Hypophosphatasia
Author:
Affiliation:
1. Alexion Pharmaceuticals, Inc. Boston Massachusetts USA
2. Orthopedic Department University of Würzburg Würzburg Bavaria Germany
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.1870
Reference27 articles.
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2. A missense mutation in the human liver/bone/kidney alkaline phosphatase gene causing a lethal form of hypophosphatasia.
3. Markedly increased circulating pyridoxal-5'-phosphate levels in hypophosphatasia. Alkaline phosphatase acts in vitamin B6 metabolism.
4. EXCRETION OF INORGANIC PYROPHOSPHATE IN HYPOPHOSPHATASIA
5. Hypophosphatasia;Rockman‐Greenberg C;Pediatr Endocrinol Rev,2013
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