Comparison of In Vitro-In Vivo Extrapolation of Biliary Clearance Using an Empirical Scaling Factor Versus Transport-Based Scaling Factors in Sandwich-Cultured Rat Hepatocytes
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference102 articles.
1. Applications of human pharmacokinetic prediction in first-in-human dose estimation;Zou;AAPS J,2012
2. Prediction of hepatic clearance in human from in vitro data for successful drug development;Chiba;AAPS J,2009
3. Sandwich-cultured hepatocytes: An in vitro model to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity;Swift;Drug Metab Rev,2010
4. Improved extrapolation of hepatobiliary clearance from in vitro sandwich cultured rat hepatocytes through absolute quantification of hepatobiliary transporters;Li;Mol Pharm,2010
5. Expression of basolateral and canalicular transporters in rat liver and cultures of primary hepatocytes;Borlak;Xenobiotica,2004
Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Quantitative Prediction of OATP-Mediated Disposition and Biliary Clearance Using Human Liver Chimeric Mice;Journal of Pharmacology and Experimental Therapeutics;2023-05-04
2. An in vitro human mammary epithelial cell permeability assay to assess drug secretion into breast milk;International Journal of Pharmaceutics: X;2022-12
3. Developing an In Vitro to In Vivo Extrapolation (IVIVE) Model to Predict Human Milk-to-Plasma Drug Concentration Ratios;Molecular Pharmaceutics;2022-06-08
4. Does Addition of Protein to Hepatocyte or Microsomal In Vitro Incubations Provide a Useful Improvement in In Vitro-In Vivo Extrapolation Predictability?;Drug Metabolism and Disposition;2022-01-27
5. Prediction of Drug Clearance from Enzyme and Transporter Kinetics;Methods in Molecular Biology;2021
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3