The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans-Reference-Cited by-同舟云学术

The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans

Published:2022-10-25 Issue:12 Volume:30 Page:2468-2476
ISSN:1930-7381
Container-title:Obesity
language:en
Short-container-title:Obesity

Author:

Hawley Nicola L.¹^ORCID,Duckham Rachel L.²³,Carlson Jenna C.⁴⁵^ORCID,Naseri Take⁶,Reupena Muagututia Sefuiva⁷,Lameko Viali⁸,Pomer Alysa¹^ORCID,Wetzel Abigail⁹,Selu Melania¹⁰,Lupematisila Vaimoana¹⁰,Unasa Folla¹⁰,Vesi Lupesina¹⁰,Fatu Tracy¹⁰,Unasa Seipepa¹⁰,Faasalele‐Savusa Kima¹⁰,Rivara Anna C.¹,Russell Emily⁵,Delany James P.¹¹,Viali Satupaitea¹²,Kershaw Erin E.¹³,Minster Ryan L.⁵^ORCID,Weeks Daniel E.⁵^ORCID,McGarvey Stephen T.⁹^ORCID

Affiliation:

1. Department of Chronic Disease Epidemiology Yale School of Public Health, Yale University New Haven Connecticut USA

2. Institute of Physical Activity and Nutrition Deakin University Melbourne Victoria Australia

3. Australian Institute for Musculoskeletal Science (AIMSS) The University of Melbourne, Western Health St Albans Victoria Australia

4. Department of Biostatistics, Graduate School of Public Health University of Pittsburgh Pittsburgh Pennsylvania USA

5. Department of Human Genetics, Graduate School of Public Health University of Pittsburgh Pittsburgh Pennsylvania USA

6. Ministry of Health Apia Samoa

7. Lutia I Puava Ae Mapu I Fagalele Apia Samoa

8. Oceania University of Medicine Apia Samoa

9. International Health Institute, Department of Epidemiology, School of Public Health Brown University Providence Rhode Island USA

10. Obesity, Lifestyle and Genetic Adaptations Study Group Apia Samoa

11. AdventHealth Translational Research Institute Orlando Florida USA

12. School of Medicine National University of Samoa Apia Samoa

13. Division of Endocrinology, Department of Medicine University of Pittsburgh Pittsburgh Pennsylvania USA

Funder

Fogarty International Center

National Heart, Lung, and Blood Institute

Publisher

Wiley

Subject

Nutrition and Dietetics,Endocrinology,Endocrinology, Diabetes and Metabolism,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/oby.23559

Reference40 articles.

1. A thrifty variant in CREBRF strongly influences body mass index in Samoans

2. A missense variant, rs373863828-A (p.Arg457Gln), of CREBRF and body mass index in Oceanic populations

3. Widespread prevalence of a CREBRF variant amongst Māori and Pacific children is associated with weight and height in early childhood

4. Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) people living in Aotearoa/New Zealand

5. Association study of CREBRF missense variant (rs373863828:G > A; p.Arg457Gln) with levels of serum lipid profile in the Pacific populations

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1. Type 2 Diabetes Prevalence, Control and Management within Fiji, Kiribati, Samoa, the Solomon Islands, Tonga, and Vanuatu: A Scoping Review with a Systematic Approach;Current Diabetes Reviews;2024-10

2. Cellular Senescence and Extracellular Vesicles in the Pathogenesis and Treatment of Obesity—A Narrative Review;International Journal of Molecular Sciences;2024-07-20

3. Advantage in Aging Cognition Associated with the CREBRF variant rs373863828 Among Samoans;GeroPsych;2024-05-22

4. Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries;Genetic Epidemiology;2022-11-09