Quantitative analysis of bone marrow fibrosis highlights heterogeneity in myelofibrosis and augments histological assessment: An Insight from a phase II clinical study of zinpentraxin alfa

Author:

Ryou Hosuk1,Sirinukunwattana Korsuk2,Wood Ruby3,Aberdeen Alan2ORCID,Rittscher Jens23456,Weinberg Olga K.7,Hasserjian Robert8,Pozdnyakova Olga9,Peale Frank10,Higgins Brian10,Lundberg Pontus11,Trunzer Kerstin11,Harrison Claire N.12,Royston Daniel13ORCID

Affiliation:

1. Nuffield Department of Medicine University of Oxford Oxford UK

2. Ground Truth Labs, Ltd. Oxford UK

3. Institute of Biomedical Engineering (IBME), Department of Engineering Science University of Oxford Oxford UK

4. Big Data Institute/Li Ka Shing Centre for Health Information and Discovery University of Oxford Oxford UK

5. Oxford NIHR Biomedical Research Centre Oxford University Hospitals NHS Foundation Trust Oxford UK

6. Ludwig Institute for Cancer Research University of Oxford Oxford UK

7. Department of Pathology University of Texas Southwestern Medical Center Dallas Texas USA

8. Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA

9. Department of Pathology and Laboratory Medicine University of Pennsylvania Philadelphia Pennsylvania USA

10. Genentech, Inc. South San Francisco California USA

11. F. Hoffmann‐La Roche, Ltd. Basel Switzerland

12. Guy's & St Thomas' NHS Foundation Trust London UK

13. Nuffield Division of Clinical Laboratory Sciences (NDCLS), Radcliffe Department of Medicine University of Oxford Oxford UK

Funder

Engineering and Physical Sciences Research Council

F. Hoffmann-La Roche

Cancer Research UK

Blood Cancer UK

Publisher

Wiley

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